[Update] New model number but features stay the same as the AVIC-W6400NEX.
Pros: Wireless Apple CarPlay, GPS Navigation included, easy to retain your factory steering wheel controls and backup camera, dual camera input, partially detachable faceplate.
Cons: Not Android Auto compatible and a smaller 6.2” touchscreen display.
First Impression: Just like the AVH-W4500NEX and AVIC-W8500, being able to use wireless Apple CarPlay is the standout feature (Android Auto is not available for this head unit). In addition this unit comes with built-in GPS navigation, which is a great option when you are in area with poor cellular reception. Considering the Pioneer AVIC-U280 add on GPS navigation unit costs $400 and for the AVIC-W6500NEX to only be $100 more than AVH-W4500NEX, this makes the W6500NEX a great value for those that want built-in GPS navigation.
However the tradeoff to get built-in GPS navigation for this price is that the W6500NEX loses some features that the W4500NEX has, most notably being able to use Android Auto either wired or wirelessly. They both use a clear resistive touchscreen but the W6500NEX uses a 6.2” display versus the 7” display on the W4500NEX. Other than that the W6500NEX, has the same features as other NEX units. You can easily retain your steering wheel controls and back up camera with an iDatalink Maestro or aftermarket wire harnesses. The built-in amplifier puts out 50W x 4 watts and for those looking to add amps it has three 4V RCA preouts.
The Verdict: For those that only use Apple CarPlay and would like to have built-in GPS navigation this is your best bet, being able to wireless use CarPlay in itself is a reason to get this head unit.